Description
Details
Product Information
PLTMax® Human Platelet Lysate is a growth factor-rich supplement that is a superior alternative to fetal bovine serum (FBS) for cell culture, including human mesenchymal stem cell (MSC) culture. PLTMax® has a proven track record of clinical use. It has been used to grow cells that have been used in hundreds of patients around the world. PLTMax® is used as a manufacturing component in the generation of adult stems cells in clinical trials in North America, Europe, South America, Middle East, Asia and Australia (Phase I to Phase III) in indications including neurology, nephrology, gastrointestinal disease, wound repair and cardiology.
- Manufactured to reduce lot-to-lot variation
- Reduced supplementation (PLTMax® is used at half the concentration of FBS)
- Contains more than 100 growth factors and proteins
- Enhances genetic stability in stem cell cultures
- Used in more than 30 clinical trials worldwide
PLTMax® Human Platelet Lysate is derived from normal human donor platelets collected at U.S. blood centers. Multiple donors units are pooled in large batch sizes and manufactured to produce a consistent product.
Addition of an anti-coagulant, such as heparin, is required to inhibit coagulation in media supplemented with PLTMax®. Add heparin to a final concentration of 2 U/mL when preparing complete medium.
Real time imaging of Adipose-derived MSCs from day 0 to day 5 of culture
Specifications
Specifications
| QTY | 100 mL |
|---|---|
| Form | Liquid |
| Storage Conditions | Store at -20°C for up to 3 years or 4°C for up to 2 weeks Thaw at: 37°C or 4°C |
| Shipping Conditions | Dry Ice |
| Specifications | Using PLTMax®
|
| Legal | PLTMax® is a trademark of Mill Creek Life Sciences, LLC. Product is manufactured by Mill Creek Life Sciences and distributed by Biological Industries USA. |
References
references
- Mader, Emily K et al. “Optimizing Patient Derived Mesenchymal Stem Cells as Virus Carriers for a Phase I Clinical Trial in Ovarian Cancer.” Journal of Translational Medicine 11 (2013): 20. PMC. Web. 28 Feb. 2017.
- Bao, Ji et al. “Serum-Free Medium and Mesenchymal Stromal Cells Enhance Functionality and Stabilize Integrity of Rat Hepatocyte Spheroids.” Cell transplantation 22.2 (2013): 299–308. PMC. Web. 28 Feb. 2017.
- Crespo-Diaz, Ruben et al. “Platelet Lysate Consisting of a Natural Repair Proteome Supports Human Mesenchymal Stem Cell Proliferation and Chromosomal Stability.” Cell Transplantation, Volume 20, Number 6, 2011, pp. 797-811(15).
Documentation
Manuals and Protocols
PLTMax® Human Platelet Lysate Technical Data Sheet- Culturing Human Mesenchymal Stem Cells using
MSC NutriStem® Basal Medium supplemented with PLTMax® Human Platelet Lysate
Product Literature
- Human Platelet Lysate Product Information Sheet
- POSTER: Expansion of MSCs for Translational Medicine using MSC NutriStem® Medium and PLTMax® Human Platelet Lysate - Shown at ISSCR 2017
- Sample Data: NutriStem® MSC Medium with PLTMax® or PLTGold® Human Platelet Lysate demonstrates superior expansion of MSCs
Webinars & Videos
Certificate of Analysis
COA's can be downloaded from Sartorius's Certificates Portal.
For certificates issued before November 15, 2021, please enter below the product lot number and click search.
