Attachment Factors

Attachment factors are structural proteins or protein-like substances that have adherent capabilities and increase cell-substrate interactions in a culture dependent attachment milieu. A number of glycoproteins have been identified that promote and/or influence in-vitro cell attachment to the surface or substratum of the culture vessel. Normal attachment, growth and development of many cell types are dependent on attachment factors and extracellular matrix (ECM) components. While some cells are able to synthesize these components, others require an exogenous source, particularly when grown in serum-free culture. The growth and differentiation of anchorage-dependent cells are often strongly influenced by either glass or plastic culture flasks utilized as a substrate. In order to facilitate attachment, cell spreading, growth, morphology, differentiation, and motility of your cells, Biological Industries offers an extensive line of attachment and matrix factors.