Webinars


Upcoming Webinar Series



December 13, 2017, 1:30 PM - 2:30 PM ET

Optimizing & Empowering the Gene Editing Revolution

Speaker: Branden Moriarity, PhD, CSO, B-MoGen Biotechnologies, Inc.

Sponsored by: Biological Industries USA




Abstract:

Over the past few decades, gene editing techniques using targeted nucleases have evolved from ZFNs, to TALENs, and now CRISPR, making the process of genome engineering easier, more efficient, and safer to perform. Moreover, some of the recent formulations of the CRISPR/Cas9 system using chemically modified gRNAs have enabled unprecedented levels of gene editing in primary human cell types. Our webinar will cover the many uses of targeted nucleases for genome engineering, the evolution of this process over the last 30 years, as well as novel uses for this technology and expert services provided by B-MoGen Biotechnologies.

Topic overview:

Genome engineering based on the use of nuclease-induced site-specific double strand breaks (DSB) in DNA relies on the cells’ innate ability to repair the DNA at the site of the DSB. This approach can be used to knock out gene function when repaired via the error prone non-homologous end joining pathway, or for targeted gene delivery or specific sequence changes when the DSB is repaired using homologous recombination.

This webinar will provide insight into:
  • Gene editing using targeted nucleases
  • Studying lethal and essential genes
  • Primary cell editing
  • Mitochondrial gene editing

 


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