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RNase-ExitusPlus™ - A solution for the decontamination of RNase
SKU: 01-897-1B



Producr Overview:

RNase-ExitusPlus™ is a non-alkaline, non-corrosive and non-carcinogenic cleansing solution that is highly active against RNase contamination. RNase-ExitusPlus™ has been demonstrated to inactivate more than 20μg of RNase A dried onto the bottom of a microcentrifuge tube. RNase-ExitusPlus™ is heat resistant.

RNase-ExitusPlus™ Advantages
  • Catalytic and cooperative effects of the components cause a very rapid nonenzymatic, non-sequence-specific degradation of protein and RNase molecules.
  • All components of RNase-ExitusPlus™ are readily biologically degradable and not harmful or toxic for humans.
  • No aggressive mineral acids or alkaline substances are used.
  • Equipment and materials are not damaged or corroded even after prolonged incubation time.
  • No organic solvents or volatile components, no toxic fumes.
  • Elevated temperatures above approx. 50°C speed up the reaction and the efficiency/activity!
  • RNase-ExitusPlus™ is ready-to-use for eliminating RNase from any surface including the interior of microcentrifuge tubes. By following a few simple decontamination instructions, RNase is completely inactivated and removed.



QTY 100 mL
Storage Conditions AMB
Shipping Conditions Room Temperature
Specifications RNase-ExitusPlus™ should be stored at room temperature; at colder temperatures a precipitate may form which is easily brought into solution at 37°C
Instructions for Use
  1. 1. The optimal incubation time for the decontamination of surfaces is 10 minutes and a temperature > 20°C.
    For full decontamination of surfaces, it is sufficient to wipe off RNase-ExitusPlus before it is completely dried up (after 10 to 15 minutes). It is not necessary to additionally clean with sterile water thereafter. This is a new feature in comparison to the traditional decontamination solutions.
  2. 2. After the solution is completely dried, there is no further decontamination reaction taking place. Hence, an incubation time longer than 30 minutes is not necessary and also not useful. In case of severe contamination, a second application of the solution is recommended for highest efficiency.
  3. 3. For removal of unwanted, dried residual traces of the reagent, we recommend removing these traces with sterile water or 10X TE buffer and a paper towel.
Detailed instructions
To decontaminate laboratory surfaces: Apply RNase-ExitusPlus directly to the lab surface. Wipe thoroughly with a paper towel, rinse with water and dry with a clean paper towel.
To decontaminate laboratory apparatus: Generously apply RNase-ExitusPlus to a paper towel and wipe all exposed surfaces of the apparatus thoroughly. Rinse with water and dry with a clean paper towel. To clean small parts, briefly soak them in RNase-ExitusPlus, rinse with water and dry.
To decontaminate plastic and glass vessels: Add ample RNase-ExitusPlus to enable coating the entire surface of the vessel by swirling or vortexing. Discard the solution and rinse vessels thoroughly two times with distilled water.
To decontaminate pipettors: Following manufacturers instructions; remove the shaft from the pipettor and remove seals and gaskets from the shaft. Soak the shaft for one minute in RNase-ExitusPlus, rinse the shaft thoroughly with water, let dry and reassemble.


Materials Safety Data Sheet

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