Cardiovascular Research

As the leading cause of death, globally, cardiovascular disease warrants an immense amount of research into potential treatment options. Stem cell-based therapies hold great promise in the possibility of regenerating functional cardiac tissue following myocardial infarction. Noor, et al. (2019) utilized cardiomyocyte differentiation protocols for hiPSCs created by Edri, et al. (2018) and Lian, et al. (2012) (incorporating small molecules such as IWP-2, IWP-4, and CHIR99021) for the creation of three-dimensional vascularized and perfusable heart patches to ultimately be applied to personalized cardiac models.